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DeCS
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Descriptor English:
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Protein Tyrosine Phosphatase, Non-Receptor Type 12
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Descriptor Spanish:
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Proteína Tirosina Fosfatasa no Receptora Tipo 12
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Descriptor Portuguese:
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Proteína Tirosina Fosfatase não Receptora Tipo 12
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Synonyms English:
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PEP PTPase
PEP Protein Tyrosine Phosphatase
PEST Enriched Phosphatase
PEST-Enriched Phosphatase
PTP-PEST
PTPase, PEP
Phosphatase, PEST-Enriched
Protein Tyrosine Phosphatase, Non Receptor Type 12
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Tree Number:
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D08.811.277.352.650.775.300.850
D12.644.360.585.850
D12.776.476.564.850
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Definition English:
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A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION. |
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History Note English:
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2008(1994)
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Allowable Qualifiers English:
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Record Number:
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52701
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Unique Identifier:
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D054594
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Occurrence in VHL:
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Similar:
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DeCS
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